Hello,
One of the major blockers for running dfx natively on drawin/arm64 is not dfx itself but rather the local replica that was bundled with it.
With the latest version of dfx 0.27.0 the local replica has been removed (see Dfx 0.27.0 is promoted) and dfx now relies on pocket-ic only.
Pocket-ic already supports running natively on arm (see Releases 路 dfinity/pocketic 路 GitHub) and we are actively working on making a native release of dfx for darwin/arm64
Stay tuned.